The 2-Minute Rule for cees dekker

The 2-Minute Rule for cees dekker

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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

‘It had been merely a matter of buying up a reserve on cell biology and starting to browse. I'd come from a environment of extremely-substantial vacuums, cryostats and quantum phenomena, and now I was Doing the job at place temperature with molecular biology kits.

Non-equilibrium folding of person DNA molecules recaptured approximately one thousand instances in the reliable condition nanopore

2010, formulated a completely new way (‘wedging transfer’) to manipulate nanostructures; initial report of DNA translocation by way of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores

SMC complexes can move Bodily roadblocks bigger than their ring dimension, indicating a nontopological system for DNA loop extrusion

Length control of unique carbon nanotubes by nanostructuring Using the scanning tunneling microscope

He also identified time to jot down numerous guides, deliver Pretty much forty thousand tweets and lead An effective research group at Delft College of Technology. ‘It doesn’t come to feel like work’, he states. ‘I’m just terribly curious.’

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Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-producing procedure

‘The concept There's this type of issue to be a beginning, a large bang, is previously a fascinating signpost to ceesdekker.net look at that there was a creator. But much more typically, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, there are actually only atoms and organic forces that we will evaluate.

1999, initial measurement with the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for a new Luttinger description of interacting electrons in nanotubes

2005, discovery with the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of very long-variety conformational improvements in Mre11/DNA restore complexes; and initially force measurements on the DNA molecule inside of a nanopore

Stable-point out nanopores have tested to generally be a shockingly versatile probe for one-molecule Assessment of DNA. I'll explain a number of our the latest conclusions – specially DNA knots – together with our endeavours to develop the abilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.